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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HADHB
All Species:
33.64
Human Site:
S285
Identified Species:
61.67
UniProt:
P55084
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55084
NP_000174.1
474
51294
S285
D
N
G
I
R
P
S
S
L
E
Q
M
A
K
L
Chimpanzee
Pan troglodytes
Q5R1W7
475
51377
S286
D
N
G
I
R
P
S
S
L
E
Q
M
A
K
L
Rhesus Macaque
Macaca mulatta
XP_001086547
482
52253
S286
D
N
G
I
R
P
S
S
L
E
Q
M
A
K
L
Dog
Lupus familis
XP_849696
475
51211
S286
D
N
G
I
R
P
S
S
L
E
Q
M
A
K
L
Cat
Felis silvestris
Mouse
Mus musculus
Q99JY0
475
51368
S286
D
N
G
I
R
P
S
S
L
E
Q
M
A
K
L
Rat
Rattus norvegicus
Q60587
475
51396
S286
D
N
G
I
R
P
S
S
L
E
Q
M
A
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509364
555
59898
S366
D
N
G
V
R
P
S
S
M
E
Q
M
A
K
L
Chicken
Gallus gallus
XP_420004
474
50831
S285
D
N
G
I
R
P
S
S
L
E
Q
M
S
K
L
Frog
Xenopus laevis
NP_001080077
470
50522
T286
P
S
S
M
E
Q
M
T
K
L
K
P
A
F
I
Zebra Danio
Brachydanio rerio
NP_956313
471
49953
M283
N
G
I
R
P
S
T
M
E
Q
M
A
K
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477378
469
50623
R284
P
E
S
L
A
K
L
R
P
A
F
V
K
P
Y
Honey Bee
Apis mellifera
XP_624164
466
50900
A284
K
L
A
K
L
K
P
A
F
V
K
P
Y
G
T
Nematode Worm
Caenorhab. elegans
P34255
448
47856
F270
L
S
S
L
K
P
A
F
V
K
P
H
G
T
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
95.2
94.3
N.A.
90.9
89.6
N.A.
75.8
83.9
82.9
78.4
N.A.
65.6
62.6
59
N.A.
Protein Similarity:
100
99.7
96.6
98.1
N.A.
96.8
97
N.A.
82.5
93.6
92.1
89.2
N.A.
79.7
78
74.2
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
86.6
93.3
6.6
0
N.A.
0
0
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
40
20
N.A.
13.3
13.3
53.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
8
0
8
8
0
8
0
8
62
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
62
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
8
0
0
8
0
0
0
8
62
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
8
8
0
8
0
0
8
0
% F
% Gly:
0
8
62
0
0
0
0
0
0
0
0
0
8
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
8
54
0
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
8
0
0
8
8
16
0
0
8
8
16
0
16
62
8
% K
% Leu:
8
8
0
16
8
0
8
0
54
8
0
0
0
8
62
% L
% Met:
0
0
0
8
0
0
8
8
8
0
8
62
0
0
0
% M
% Asn:
8
62
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
16
0
0
0
8
70
8
0
8
0
8
16
0
8
0
% P
% Gln:
0
0
0
0
0
8
0
0
0
8
62
0
0
0
0
% Q
% Arg:
0
0
0
8
62
0
0
8
0
0
0
0
0
0
0
% R
% Ser:
0
16
24
0
0
8
62
62
0
0
0
0
8
0
0
% S
% Thr:
0
0
0
0
0
0
8
8
0
0
0
0
0
8
8
% T
% Val:
0
0
0
8
0
0
0
0
8
8
0
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _